WHAT IS PEPTAIM?
PeptAIm - Virtual Phage Display is a novel technology that replaces the need to use standard laboratory methods such as phage display by combining artificial intelligence and machine learning for accurate predictions of protein-protein interaction. This platform gives a possibility to design short peptides that have the highest affinity to targeted protein to be further used in diagnostics, therapy and basic science.
PeptAIm provides an easy and quick solution for detecting high-affinity peptides for any given receptor (sequence or structure). The PeptAIm platform is built around an experimentally validated algorithm that uses machine learning (ML) and artificial intelligence (AI). By optimizing virtual high-throughput screening (vHTS) PeptAIm allows for molecular docking of virtual peptide libraries, which include all possible amino acid (AA) sequence combinations for a particular peptide length (4-12 AAs). Furthermore, with ML and AI support, our algorithm reduces the cost, time, and computational power necessary for such analyses while also allowing for the exploration of a large portion of the peptide chemical space.
PeptAIm - Virtual Phage Display is a revolutionary technology that eliminates the need for conventional laboratory methods like phage display. PeptAIm is a simple and efficient bioinformatic platform for identifying high-affinity peptides for any given receptor (structure or sequence). The PeptAIm platform is designed around an experimentally validated algorithm that employs machine learning (ML) and artificial intelligence (AI). By enhancing virtual high-throughput screening (vHTS), PeptAIm enables molecular docking of virtual peptide libraries, which encompass all possible amino acid (AA) sequence combinations for a given peptide length (4-12 AAs). Furthermore, with ML and AI support, our algorithm lowers the cost, time, and processing power required for such investigations while allowing for exploration of a vast percentage of the peptide chemical space.
HOW DOES IT WORK?
Submit your own sequence, structure, or any protein structure directly from the Protein Data Bank database.
The PeptAIm algorithm will scan the protein surface to discover binding sites.
Peptide-ligand candidates will be automatically searched, proposed, and docked with the receptor.
Our specialists confirm the accuracy of the results and generate a complete report of the top n candidates for the particular receptor.
The service can be extended to include laboratory validation and synthesis of the specified ligands.
All aspects of virtual screening, including iterative molecular docking studies and peptide library exploration, are performed automatically. The study produces a report containing a list of top candidate peptides that may bind to target proteins and be employed in molecular diagnosis, as well as the most significant information about their structures and binding mode.
ARE YOU INTERESTED?
NanoExpo experts offer comprehensive services for identifying high-affinity peptides for any given receptor (sequence or structure), followed by laboratory validation and peptide synthesis. Contact us for more information at info@nanoexpo.eu.
