Patents
Nucleotide sequences encoding the amino acid sequences of the recombinant biological nanostructure and platforms for the introduction and exposure of foreign antigens, the amino acid sequences of the recombinant biological nanostructure and platforms containing restriction sites for the introduction and exposure of foreign antigens, primers for introducing antigens into the restriction sequences, and the use of amino acid sequences for the exposure of foreign antigens, especially as a humoral response inducing immunogen, in the production of antibodies and reference antigens in diagnostics; Inventors: Beata Gromadzka, Mirosława Panasiuk, Karolina Zimmer, Polish nr. P.432182, European nr. PCT/PL2019/050078
Orsay virus-based biological nanostructures to introduce and present foreign antigens; biological platforms to present foreign antigens including nanostructures, primers to introduce antigens into platforms, and application of nanostructures and platforms to present foreign antigens in manufacturing antibodies, reference antigens and/or next generation therapeutics, including vaccines and carriers to produce drugs. Inventors: Beata Gromadzka, Mirosława Panasiuk, Karolina Zimmer, Weronika Hoffmann, Stanisław Ołdziej, CTT 20/2019/CTT/Z
Papers
Panasiuk M, Zimmer K, Czarnota A, Grzyb K, Narajczyk M, Peszyńska-Sularz G, Żołędowska S, Nidzworski D, Hovhannisyan L, Gromadzka B. Immunization with Leishmania tarentolae-derived norovirus virus-like particles elicits high humoral response and stimulates the production of neutralizing antibodies. Microb Cell Fact. 2021 Sep 24;20(1):186. doi: 10.1186/s12934-021-01677-1. PMID: 34560881; PMCID: PMC8464126.
Naskalska A, Dabrowska A, Szczepanski A, Jasik KP, Gromadzka B, Pyrc K. Functional Severe Acute Respiratory Syndrome Coronavirus 2 Virus-Like Particles From Insect Cells. Front Microbiol. 2021 Oct 20;12:732998. doi: 10.3389/fmicb.2021.732998. PMID: 34745036; PMCID: PMC8565087.
Janczuk-Richter, M.; Gromadzka, B.; Richter, Ł.; Panasiuk, M.; Zimmer, K.; Mikulic, P.; Bock, W.J.; Maćkowski, S.; Śmietana, M.; Niedziółka Jönsson, J. Immunosensor Based on Long-Period Fiber Gratings for Detection of Viruses Causing Gastroenteritis. Sensors 2020, 20, 813. https://doi.org/10.3390/s20030813.
